https://ogma.newcastle.edu.au/vital/access/ /manager/Index en-au 5 https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:45222 Wed 26 Oct 2022 15:50:17 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:37886 3 seconds and with clinical outcome measured using 3-month modified Rankin Scale. Results: A total of 732 ischemic stroke patients underwent computed tomography, 231 with transthoracic echocardiogram were included in part (1), 393 with outcome data were included in part (2). In part (1), 193/231 (83.5%) had normal LVEF (median 61%) and 38/231 (16.5%) decreased LVEF (median 39%). The low-LVEF group had significantly prolonged SO-EndAIF compared with normal-LVEF group (mean of 39.7 versus 26 second; P<0.001), and larger hypoperfusion lesions (94.9 versus 37.6 mL; P<0.001). SO-EndAIF time was strongly associated with EF, with an area under the curve of 0.86. Twenty nine seconds was the best threshold to distinguish between normal and impaired EF (area under the curve, 0.77). In part (2), the SO-EndAIF ≥29 second group had larger hypoperfusion volumes (21.8 versus 89.7 mL; P<0.001) and infarct core (12.2 versus 2.3 mL; P<0.0001) and patients with SO-EndAIF ≥29 seconds had fewer excellent or good clinical outcomes (modified Rankin Scale score 0–1; 40% versus 22%; OR, 2.79; P<0.001, modified Rankin Scale score 0–2; 65% versus 35%; OR, 1.41; P=0.033). Conclusions: AIF width correlates with ejection fraction in acute ischemic stroke. A 29-second threshold from scan onset to end of AIF accurately predicts reduced LVEF and identifies patients more likely to have worse outcomes after stroke.]]> Wed 17 Nov 2021 16:29:40 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:38703 Wed 06 Jul 2022 10:42:43 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:38503 Thu 18 Nov 2021 09:53:11 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:50542 Fri 18 Aug 2023 12:00:25 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:41805 Fri 12 Aug 2022 12:31:27 AEST ]]>